ERBB2(D769Y)

26382

Size：100 μl Price：$ 495 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

ERBB2(D769Y)

Cat. #: 26382

Gene Symbol: ERBB2/HER2/Neu/c-Neu

Description: Anti-ERBB2(D769Y) Mouse Monoclonal Antibody

Background: The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer.

Immunogen: A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769Y, human origin.

Applications: ELISA, IF, IHC

Recommended Dilutions: ELISA: 1:1000-1:2000 IF: 1:500-1:1000 IHC: 1:50-1:100

Concentration: 1 mg/ml

Host Species: Mouse

Format: Liquid

Clonality: Monoclonal

Isotype: IgG

Purity: Purified from ascites

Preservative: No

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Recognizes D769Y mutant, but not wild type ERBB2 of vertebrates.

Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence:

Immunofluorescence of cells expressing ERBB2 proteins with Anti-ERBB2(D769Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-ERBB2(D769Y) plasmid, pCDNA3-GFP-ERBB2 (WT) plasmid or pCDNA3-GFP-ERBB2 (D769H) plasmid, then fixed and stained with Anti-ERBB2(D769Y) monoclonal antibody (Cat. #26382).

Reference citations

No data available

Product Targets

Product Categories

ERBB2(D769Y)

IDH2(R172G)

IDH2(R172W)

IDH2(R172K)

IDH2(R172S)

Contant Us