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Size:100 μl Price:$ 239 Brand:NewEast Place of Origin:USA Immunogen:
STK11 Antibody
Cat. #: 26158 |
Size: 100 µL |
Gene Symbol: STK11, LKB1, PJS, hLKB1 |
Description: Anti-STK11 Mouse Monoclonal Antibody |
Background: Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer. |
Immunogen: A synthetic peptide from the internal region of STK, which includes the mutation of P281L, human origin. |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:100-1:1000 IHC: 1:50-1:200 |
Concentration: 0.5 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Recognizes P281L mutated, but not wild type STK11 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |
Immunofluorescence: Immunofluorescence of cells expressing STK11 proteins with Anti-STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP-STK11 (WT) plasmid (left column) or pCDNA3-GFP-STK11 (P281L) plasmid (right column), then fixed and stained with Anti-STK11 (P281L) monoclonal antibody (Cat. #26158). |
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