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GM-CSF mAb (Plonmarlimab)

28125

Size:100 μg Price:$ 199 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:   28125
Product Name:   Anti-GM-CSF(Plonmarlimab) Monoclonal Antibody
Synonyms:   CSF;CSF2
Description:    Anti-GM-CSF(plonmarlimab ) Monoclonal Antibody
Background:    Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
Applications:    ELISA; Flow Cyt
Recommended Dilutions:    ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:    Humanized
Isotype:    IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human GM-CSF
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. ELISA plate pre-coated by 2 µg/mL (100 µl/well) Human GM-CSF Protein, hFc Tag (11365) can bind Anti-GM-CSF Neutralizing antibody (28125) in a linear range of 0.92-937.50 ng/mL. In order to specifically detect 28125, mouse anti-human Fab-specific antibody was used as detection antibody.

Figure 2. Flow cytometry analysis under cell membrane permeable condition with 1 µg/mL Anti-GM-CSF (plonmarlimab biosimilar) mAb (28125) on Expi293 cells transfected with Human GM-CSF protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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