BCL2L2 Rabbit pAb

210088

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210088

Product Name: Anti-BCL2L2 Rabbit Polyclonal Antibody

Synonyms: BCLW; BCL-W; PPP1R51; BCL2-L-2

UNIPROT ID: Q92843 (Gene Accession - BC113522 )

Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Immunogen: Fusion protein of human BCL2L2

Applications: ELISA, IHC

Recommended Dilutions: IHC: 15-50; ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 210088(BCL2L2 Antibody) at a dilution of 1/15(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the fusion protein and then with 210088(Anti-BCL2L2 Antibody) at dilution 1/15.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 210088(Anti-BCL2L2 Antibody) at a dilution of 1/15.	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D120152(Anti-BCL2L2 Antibody) at dilution 1/15.

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