CYP1B1 Rabbit pAb

210262

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210262

Product Name: Anti-CYP1B1 Rabbit Polyclonal Antibody

Synonyms: CP1B; GLC3A; CYPIB1; P4501B1

UNIPROT ID: Q16678 (Gene Accession - BC012049 )

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

Immunogen: Fusion protein of human CYP1B1

Applications: ELISA, IHC

Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Metabolism, Neuroscience, Cardiovascular

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 210262(CYP1B1 Antibody) at a dilution of 1/20(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 210262(Anti-CYP1B1 Antibody) at dilution 1/20.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 210262(Anti-CYP1B1 Antibody) at a dilution of 1/20.	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D120519(Anti-CYP1B1 Antibody) at dilution 1/20.

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