ITGB3BP Rabbit pAb

210395

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210395

Product Name: Anti-ITGB3BP Rabbit Polyclonal Antibody

Synonyms: CENPR, NRIF3, TAP20, CENP-R, HSU37139

UNIPROT ID: Q13352 (Gene Accession - BC014385 )

Background: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Immunogen: Fusion protein of human ITGB3BP

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction, Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human gasrtic cancer tissue using 210395(ITGB3BP Antibody) at a dilution of 1/50(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human brain tissue using 210395(Anti-ITGB3BP Antibody) at a dilution of 1/50.

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ITGB3BP Rabbit pAb

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