COPS5 Rabbit pAb

210411

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210411

Product Name: Anti-COPS5 Rabbit Polyclonal Antibody

Synonyms: CSN5, JAB1, SGN5, MOV-34

UNIPROT ID: Q92905 (Gene Accession - BC001187 )

Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors

Immunogen: Fusion protein of human COPS5

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 150-500;WB: 1000-5000;ELISA: 2000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling, Cancer, Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 210411(COPS5 Antibody) at a dilution of 1/120(Cytoplasm, Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 210411(Anti-COPS5 Antibody) at dilution 1/120.
Gel: 12%SDS-PAGE, Lysate: 30 μg; Lane: Mouse liver tissue; Primary antibody: 210411(COPS5 Antibody) at dilution 1/1550; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 5 seconds

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COPS5 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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