RRM1 Rabbit pAb

210551

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210551

Product Name: Anti-RRM1 Rabbit Polyclonal Antibody

Synonyms: R1; RR1; RIR1

UNIPROT ID: P23921 (Gene Accession - BC006498 )

Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Immunogen: Fusion protein of human RRM1

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 25-100;WB: 200-1000;ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 210551(RRM1 Antibody) at a dilution of 1/15(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 210551(Anti-RRM1 Antibody) at dilution 1/15.
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 210551(Anti-RRM1 Antibody) at a dilution of 1/15.	In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D121160(Anti-RRM1 Antibody) at dilution 1/15.
Gel: 10%SDS-PAGE, Lysate: 50 μg; Lane 1-2: Hela cells, 231 cells; Primary antibody: 210551(RRM1 Antibody) at dilution 1/200; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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RRM1 Rabbit pAb

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TUBA4A Rabbit pAb

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