PHF6 Rabbit pAb

210554

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210554

Product Name: Anti-PHF6 Rabbit Polyclonal Antibody

Synonyms: BFLS; BORJ; CENP-31

UNIPROT ID: Q8IWS0 (Gene Accession - BC005994 )

Background: This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Immunogen: Fusion protein of human PHF6

Applications: ELISA, IHC

Recommended Dilutions: IHC: 100-300; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 210554(PHF6 Antibody) at a dilution of 1/85(Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 210554(Anti-PHF6 Antibody) at dilution 1/85.
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 210554(Anti-PHF6 Antibody) at a dilution of 1/85.	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D121165(Anti-PHF6 Antibody) at dilution 1/85.

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