TNFRSF1B Rabbit pAb

210639

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210639

Product Name: Anti-TNFRSF1B Rabbit Polyclonal Antibody

Synonyms: p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II

UNIPROT ID: P20333 (Gene Accession - BC052977 )

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Immunogen: Fusion protein of human TNFRSF1B

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-100;WB: 500-2000;ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction, Cardiovascular, Cancer, Neuroscience, Immunology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 210639(TNFRSF1B Antibody) at a dilution of 1/70(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 210639(Anti-TNFRSF1B Antibody) at dilution 1/70.
Gel: 8%SDS-PAGE, Lysate: 40 μg; Lane 1-3: 293T, Hela, MCF7 cell lysates; Primary antibody: 210639(TNFRSF1B Antibody) at dilution 1/1000; Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution; Exposure time: 20 seconds

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TNFRSF1B Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

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