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GMFG Rabbit pAb

210890

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:   S210890
Product Name:   Anti-GMFG Rabbit Polyclonal Antibody
Synonyms:   GMF-GAMMA
UNIPROT ID:   O60234 (Gene Accession - BC080180 )
Background:    Glia maturation factor, gamma, also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.
Immunogen:    Fusion protein of human GMFG
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 210890(GMFG Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 210890(Anti-GMFG Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 210890(Anti-GMFG Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D121824(Anti-GMFG Antibody) at dilution 1/50.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart tissue, human fetal brain tissue;
Primary antibody: 210890(GMFG Antibody) at dilution 1/1142;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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