ASGR1 Rabbit pAb

210936

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210936

Product Name: Anti-ASGR1 Rabbit Polyclonal Antibody

Synonyms: HL-1; ASGPR; ASGPR1; CLEC4H1

UNIPROT ID: P07306 (Gene Accession - BC032130 )

Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen: Fusion protein of human ASGR1

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 210936(ASGR1 Antibody) at a dilution of 1/50(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 210936(Anti-ASGR1 Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 210936(Anti-ASGR1 Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D121918(Anti-ASGR1 Antibody) at dilution 1/50.
Gel: 8%SDS-PAGE, Lysate: 50 μg; Lane: 231 cells; Primary antibody: 210936(ASGR1 Antibody) at dilution 1/300; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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ASGR1 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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