ANKHD1 Rabbit pAb

210949

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S210949

Product Name: Anti-ANKHD1 Rabbit Polyclonal Antibody

Synonyms: MASK; VBARP; PP2500

UNIPROT ID: Q8IWZ3 (Gene Accession - BC009420 )

Background: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

Immunogen: Fusion protein of human ANKHD1

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction, Cancer, Immunology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 210949(ANKHD1 Antibody) at a dilution of 1/40(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 210949(Anti-ANKHD1 Antibody) at dilution 1/40.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 210949(Anti-ANKHD1 Antibody) at a dilution of 1/40.	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D121942(Anti-ANKHD1 Antibody) at dilution 1/40.

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