IMPDH2 Rabbit pAb

211296

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S211296

Product Name: Anti-IMPDH2 Rabbit Polyclonal Antibody

Synonyms: IMPD2; IMPDH-II

UNIPROT ID: P12268 (Gene Accession - BC006124 )

Background: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Immunogen: Fusion protein of human IMPDH2

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 500-2000;ELISA: 2000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Metabolism, Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 211296(IMPDH2 Antibody) at a dilution of 1/60(Cytoplasm or Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 211296(Anti-IMPDH2 Antibody) at dilution 1/60.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 211296(Anti-IMPDH2 Antibody) at a dilution of 1/60.	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D122546(Anti-IMPDH2 Antibody) at dilution 1/60.
Gel: 8%SDS-PAGE, Lysate: 40 μg; Lane: A549 cells; Primary antibody: 211296(IMPDH2 Antibody) at dilution 1/650; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 3 minutes

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IMPDH2 Rabbit pAb

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