TRIM74 Rabbit pAb

211689

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S211689

Product Name: Anti-TRIM74 Rabbit Polyclonal Antibody

Synonyms: TRIM50C

UNIPROT ID: Q86UV6 (Gene Accession - BC033871 )

Background: TRIM 74 (Tripartite motif-containing protein 74) is a possible protein coding regions found at gene location 7q11.23. Tripartite motif (TRIM) proteins play important roles in a variety of cellular functions including cell proliferation, differentiation, development, oncogenesis, and apoptosis. TRIM gene expression analysis in primary human immune cells seem to suggest the involvement of TRIM proteins in also regulating host antiviral activities. The gene encoding TRIM 74 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Immunogen: Full length fusion protein

Applications: ELISA, IHC

Recommended Dilutions: IHC: 30-150; ELISA: 2000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 211689(TRIM74 Antibody) at a dilution of 1/45(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 211689(Anti-TRIM74 Antibody) at dilution 1/45.

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TRIM74 Rabbit pAb

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