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RIMKLB Rabbit pAb

211830

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S211830
Product Name:   Anti-RIMKLB Rabbit Polyclonal Antibody
Synonyms:   NAAGS; FAM80B; NAAGS-I
UNIPROT ID:   Q9ULI2 (Gene Accession - BC033793 )
Background:    RIMKLB (ribosomal modification protein rimK-like family member B), also known as NAAGS (N-acetyl-aspartyl-glutamate synthetase B), beta-citryl-glutamate synthase B or FAM80B, is a 386 amino acid cytoplasmic protein that belongs to the rimK family. Acting as the catalyst in the synthesis of beta-citryl-glutamate and N-acetyl-aspartyl-glutamate, RIMKLB contains one ATP-grasp domain and exists as two alternatively spliced isoforms. The gene encoding RIMKLB maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Immunogen:    Full length fusion protein
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 211830(RIMKLB Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 211830(Anti-RIMKLB Antibody) at dilution 1/30.
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