Email Us：info@neweastbio.com
Call Us：(+1) 610-945-2007
Email Us：info@neweastbio.com
Call Us：(+1) 610-945-2007
Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S211955 | ||||
| Product Name: Anti-GCLC Rabbit Polyclonal Antibody | ||||
| Synonyms: GCL; GCS; GLCL; GLCLC | ||||
| UNIPROT ID: P48506 (Gene Accession - BC022487 ) | ||||
| Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. | ||||
| Immunogen: Fusion protein of human GCLC | ||||
| Applications: ELISA, WB, IHC | ||||
| Recommended Dilutions: IHC: 50-200;WB: 500-2000;ELISA: 5000-10000 | ||||
| Host Species: Rabbit | ||||
| Clonality: Rabbit Polyclonal | ||||
| Isotype: Immunogen-specific rabbit IgG | ||||
| Purification: Antigen affinity purification | ||||
| Species Reactivity: Human, Mouse, Rat | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
| Research Areas: Metabolism, Cell Biology | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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