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Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S212166 | ||||||
| Product Name: Anti-CNTNAP2 Rabbit Polyclonal Antibody | ||||||
| Synonyms: CDFE; NRXN4; AUTS15; CASPR2; PTHSL1 | ||||||
| UNIPROT ID: Q9UHC6 (Gene Accession - BC113373 ) | ||||||
| Background: This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation. | ||||||
| Immunogen: Fusion protein of human CNTNAP2 | ||||||
| Applications: ELISA, WB, IHC | ||||||
| Recommended Dilutions: IHC: 20-100;WB: 200-1000;ELISA: 5000-10000 | ||||||
| Host Species: Rabbit | ||||||
| Clonality: Rabbit Polyclonal | ||||||
| Isotype: Immunogen-specific rabbit IgG | ||||||
| Purification: Antigen affinity purification | ||||||
| Species Reactivity: Human, Mouse, Rat | ||||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
| Research Areas: Neuroscience | ||||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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