SH3GLB2 Rabbit pAb

213237

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213237

Product Name: Anti-SH3GLB2 Rabbit Polyclonal Antibody

Synonyms: RRIG1; PP6569; PP9455

UNIPROT ID: Q9NR46 (Gene Accession - BC014635 )

Background: The Endophilins comprise a family of proteins that associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse. Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis.

Immunogen: Fusion protein of human SH3GLB2

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-100; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cell Biology, Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 213237(SH3GLB2 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 213237(Anti-SH3GLB2 Antibody) at dilution 1/50.

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