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ZFYVE19 ? Rabbit pAb

213323

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S213323
Product Name:   Anti-ZFYVE19 Rabbit Polyclonal Antibody
Synonyms:   MPFYVE
UNIPROT ID:   Q96K21 (Gene Accession - NP_001070736 )
Background:    ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events.
Immunogen:    Synthetic peptide of human ZFYVE19
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 213323(ZFYVE19 Antibody) at a dilution of 1/61(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 213323(Anti-ZFYVE19 Antibody) at dilution 1/61.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 213323(Anti-ZFYVE19 Antibody) at a dilution of 1/61.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D156029(Anti-ZFYVE19 Antibody) at dilution 1/61.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Hela cells, A431 cells;
Primary antibody: 213323(ZFYVE19 Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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