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Call Us：(+1) 610-945-2007
Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: S213335 | ||||||
| Product Name: Anti-ABCG2 Rabbit Polyclonal Antibody | ||||||
| Synonyms: MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; GOUT1; MXR-1; CDw338; UAQTL1; EST157481 | ||||||
| UNIPROT ID: Q9UNQ0 (Gene Accession - NP_004818 ) | ||||||
| Background: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. | ||||||
| Immunogen: Synthetic peptide of human ABCG2 | ||||||
| Applications: ELISA, WB, IHC | ||||||
| Recommended Dilutions: IHC: 50-100;WB: 200-1000;ELISA: 5000-10000 | ||||||
| Host Species: Rabbit | ||||||
| Clonality: Rabbit Polyclonal | ||||||
| Isotype: Immunogen-specific rabbit IgG | ||||||
| Purification: Antigen affinity purification | ||||||
| Species Reactivity: Human | ||||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
| Research Areas: Metabolism, Cancer, Stem Cells | ||||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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