PRKAB1 Rabbit pAb

213351

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: S213351

Product Name: Anti-PRKAB1 Rabbit Polyclonal Antibody

Synonyms: AMPK, HAMPKb

UNIPROT ID: Q9Y478 (Gene Accession - NP_006244 )

Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

Immunogen: Synthetic peptide of human PRKAB1

Applications: ELISA, IHC

Recommended Dilutions: IHC: Oct-50; ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Metabolism, Signal Transduction, Cancer, Cardiovascular

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human stomach cancer tissue using 213351(PRKAB1 Antibody) at a dilution of 1/15(Cytoplasm ).	In comparision with the IHC on the left, the same paraffin-embedded Human stomach cancer tissue is first treated with the synthetic peptide and then with 213351(Anti-PRKAB1 Antibody) at dilution 1/15.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 213351(Anti-PRKAB1 Antibody) at a dilution of 1/15.	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D160046(Anti-PRKAB1 Antibody) at dilution 1/15.

Reference citations

No data available

Product Targets

Product Categories

PRKAB1 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

Contant Us