FGF4 Rabbit pAb

213399

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213399

Product Name: Anti-FGF4 Rabbit Polyclonal Antibody

Synonyms: HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-4

UNIPROT ID: P08620 (Gene Accession - NP_001998 )

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Immunogen: Synthetic peptide of human FGF4

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-150; ELISA: 1000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction, Cancer, Cardiovascular

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213399(FGF4 Antibody) at a dilution of 1/40(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213399(Anti-FGF4 Antibody) at dilution 1/40.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 213399(Anti-FGF4 Antibody) at a dilution of 1/40.	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D160125(Anti-FGF4 Antibody) at dilution 1/40.

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