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POU2AF1 Rabbit pAb

213403

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S213403
Product Name:   Anti-POU2AF1 Rabbit Polyclonal Antibody
Synonyms:   BOB1, OBF1, OCAB, OBF-1
UNIPROT ID:   Q16633 (Gene Accession - NP_006226 )
Background:    POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene. POU2AF1 has been shown to interact with POU2F1 and SIAH1. POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It encourages the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is necessary for the response of B-cells to antigens and required for the formation of germinal centers.
Immunogen:    Synthetic peptide of human POU2AF1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 213403(POU2AF1 Antibody) at a dilution of 1/15(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 213403(Anti-POU2AF1 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 213403(Anti-POU2AF1 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D160130(Anti-POU2AF1 Antibody) at dilution 1/15.
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