CDKN1C Rabbit pAb

213422

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213422

Product Name: Anti-CDKN1C Rabbit Polyclonal Antibody

Synonyms: BWS; WBS; p57; BWCR; KIP2; p57Kip2

UNIPROT ID: P49918 (Gene Accession - NP_000067 )

Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Immunogen: Synthetic peptide of human CDKN1C

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling, Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 213422(CDKN1C Antibody) at a dilution of 1/50(Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 213422(Anti-CDKN1C Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 213422(Anti-CDKN1C Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D160160(Anti-CDKN1C Antibody) at dilution 1/50.

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