SLC1A2 Rabbit pAb

213488

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213488

Product Name: Anti-SLC1A2 Rabbit Polyclonal Antibody

Synonyms: EAAT2, GLT-1

UNIPROT ID: P43004 (Gene Accession - NP_004162 )

Background: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.

Immunogen: Synthetic peptide of human SLC1A2

Applications: ELISA, IHC

Recommended Dilutions: IHC: 25-100; ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Metabolism, Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 213488(SLC1A2 Antibody) at a dilution of 1/20(Cytoplasm, Cell membrane).	In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 213488(Anti-SLC1A2 Antibody) at dilution 1/20.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 213488(Anti-SLC1A2 Antibody) at a dilution of 1/20.	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D160280(Anti-SLC1A2 Antibody) at dilution 1/20.

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