FOXO1 Rabbit pAb

213527

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: S213527

Product Name: Anti-FOXO1 Rabbit Polyclonal Antibody

Synonyms: FKH1, FKHR, FOXO1A

UNIPROT ID: Q12778 (Gene Accession - NP_002006 )

Background: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import.

Immunogen: Synthetic peptide of human FOXO1

Applications: ELISA, IHC

Recommended Dilutions: IHC: 25-100; ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cardiovascular, Epigenetics and Nuclear Signaling, Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 213527(FOXO1 Antibody) at a dilution of 1/20(Cytoplasm or Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 213527(Anti-FOXO1 Antibody) at dilution 1/20.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 213527(Anti-FOXO1 Antibody) at a dilution of 1/20.	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D160363(Anti-FOXO1 Antibody) at dilution 1/20.

Reference citations

No data available

Product Targets

Product Categories

FOXO1 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

Contant Us