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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: S213558 |
Product Name: Anti-GJB2 Rabbit Polyclonal Antibody |
Synonyms: HID; KID; PPK; BAPS; CX26; DFNA3; DFNB1; NSRD1; DFNA3A; DFNB1A |
UNIPROT ID: P29033 (Gene Accession - NP_003995 ) |
Background: This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. |
Immunogen: Synthetic peptide of human GJB2 |
Applications: ELISA, IHC |
Recommended Dilutions: IHC: 100-300; ELISA: 1000-10000 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Isotype: Immunogen-specific rabbit IgG |
Purification: Antigen affinity purification |
Species Reactivity: Human, Rat |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
Research Areas: Signal Transduction, Neuroscience |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using 213558(GJB2 Antibody) at a dilution of 1/100(Cytoplasm). |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase