GFRA1 Rabbit pAb

213567

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: S213567

Product Name: Anti-GFRA1 Rabbit Polyclonal Antibody

Synonyms: GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1

UNIPROT ID: P56159 (Gene Accession - NP_005255 )

Background: This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Immunogen: Synthetic peptide of human GFRA1

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 500-2000;ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 213567(GFRA1 Antibody) at a dilution of 1/65(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 213567(Anti-GFRA1 Antibody) at dilution 1/65.
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 213567(Anti-GFRA1 Antibody) at a dilution of 1/65.	In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D160424(Anti-GFRA1 Antibody) at dilution 1/65.
Gel: 8%SDS-PAGE, Lysate: 40 μg; Lane: Rat brain tissue lysate; Primary antibody: 213567(GFRA1 Antibody) at dilution 1/800; Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution; Exposure time: 90 seconds

Reference citations

No data available

Product Targets

Product Categories

GFRA1 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

Contant Us