HMGA1 Rabbit pAb

213596

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213596

Product Name: Anti-HMGA1 Rabbit Polyclonal Antibody

Synonyms: HMG-R, HMGIY, HMGA1A

UNIPROT ID: P17096 (Gene Accession - NP_665906 )

Background: This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

Immunogen: Synthetic peptide of human HMGA1

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 2000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling, Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 213596(HMGA1 Antibody) at a dilution of 1/30(Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 213596(Anti-HMGA1 Antibody) at dilution 1/30.
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 213596(Anti-HMGA1 Antibody) at a dilution of 1/30.	In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D160486(Anti-HMGA1 Antibody) at dilution 1/30.

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