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MAGEA6 Rabbit pAb

213647

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S213647
Product Name:   Anti-MAGEA6 Rabbit Polyclonal Antibody
Synonyms:   CT1.6; MAGE6; MAGE3B; MAGE-3b
UNIPROT ID:   P43360 (Gene Accession - NP_005354 )
Background:    This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human MAGEA6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213647(MAGEA6 Antibody) at a dilution of 1/120(nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213647(Anti-MAGEA6 Antibody) at dilution 1/120.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 213647(Anti-MAGEA6 Antibody) at a dilution of 1/120.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D160581(Anti-MAGEA6 Antibody) at dilution 1/120.
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