PDK2 Rabbit pAb

213711

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213711

Product Name: Anti-PDK2 Rabbit Polyclonal Antibody

Synonyms: PDHK2

UNIPROT ID: Q15119 (Gene Accession - NP_002602 )

Background: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen: Synthetic peptide of human PDK2

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Metabolism, Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213711(PDK2 Antibody) at a dilution of 1/40(Mitochondrion matri,x Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213711(Anti-PDK2 Antibody) at dilution 1/40.
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 213711(Anti-PDK2 Antibody) at a dilution of 1/40.	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D160702(Anti-PDK2 Antibody) at dilution 1/40.
Gel: 10%SDS-PAGE, Lysate: 50 μg; Lane: Mouse heart tissue; Primary antibody: 213711(PDK2 Antibody) at dilution 1/500; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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PDK2 Rabbit pAb

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