PRDX3 Rabbit pAb

213722

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213722

Product Name: Anti-PRDX3 Rabbit Polyclonal Antibody

Synonyms: AOP1, MER5, AOP-1, SP-22, HBC189, PRO1748, prx-III

UNIPROT ID: P30048 (Gene Accession - NP_006784 )

Background: This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Immunogen: Synthetic peptide of human PRDX3

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 1000-5000;ELISA: 2000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction, Cancer, Metabolism, Neuroscience, Cardiovascular

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213722(PRDX3 Antibody) at a dilution of 1/50(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213722(Anti-PRDX3 Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 213722(Anti-PRDX3 Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D160719(Anti-PRDX3 Antibody) at dilution 1/50.
Gel: 10%SDS-PAGE, Lysate: 40 μg; Lane 1-2: Hela cells, 293T cells; Primary antibody: 213722(PRDX3 Antibody) at dilution 1/800; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 20 seconds

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PRDX3 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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