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FZD2 Rabbit pAb

213774

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:   S213774
Product Name:   Anti-FZD2 Rabbit Polyclonal Antibody
Synonyms:   Fz2; fz-2; fzE2; hFz2
UNIPROT ID:   Q14332 (Gene Accession - NP_001457.1 )
Background:    This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
Immunogen:    Synthetic peptide of human FZD2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human renal cancer tissue using 213774(FZD2 Antibody) at a dilution of 1/25(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human renal cancer tissue is first treated with the synthetic peptide and then with 213774(Anti-FZD2 Antibody) at dilution 1/25.
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