PAK1 Rabbit pAb

213924

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213924

Product Name: Anti-PAK1 Rabbit Polyclonal Antibody

Synonyms: PAKalpha

UNIPROT ID: Q13153 (Gene Accession - NP_001122092 )

Background: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: Synthetic peptide of human PAK1

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 25-100;WB: 500-2000;ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction, Cancer, Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213924(PAK1 Antibody) at a dilution of 1/40(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213924(Anti-PAK1 Antibody) at dilution 1/40.
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 213924(Anti-PAK1 Antibody) at a dilution of 1/40.	In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D161067(Anti-PAK1 Antibody) at dilution 1/40.
Gel: 10%SDS-PAGE, Lysate: 40 μg; Lane 1-2: 293T cells, K562 cells; Primary antibody: 213924(PAK1 Antibody) at dilution 1/700; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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PAK1 Rabbit pAb

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