PLAT Rabbit pAb

213973

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S213973

Product Name: Anti-PLAT Rabbit Polyclonal Antibody

Synonyms: TPA, T-PA

UNIPROT ID: P00750 (Gene Accession - NP_000921 )

Background: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Immunogen: Synthetic peptide of human PLAT

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 213973(PLAT Antibody) at a dilution of 1/50(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 213973(Anti-PLAT Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 213973(Anti-PLAT Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D161138(Anti-PLAT Antibody) at dilution 1/50.
Gel: 8%SDS-PAGE, Lysate: 40 μg; Lane: 231 cells; Primary antibody: 213973(PLAT Antibody) at dilution 1/450; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 10 minutes

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PLAT Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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