CASP9 (active) Rabbit pAb

214033

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S214033

Product Name: Anti-CASP9 (active) Rabbit Polyclonal Antibody

Synonyms: MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; CASPASE-9c

UNIPROT ID: P55211 (Gene Accession - NP_001220 )

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.

Immunogen: Synthetic peptide of human CASP9 (active)

Applications: ELISA, IHC

Recommended Dilutions: IHC: 100-300; ELISA: 2000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cancer

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 214033(CASP9 (active) Antibody) at a dilution of 1/80(Nucleus, Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 214033(Anti-CASP9 (Anti-active) Antibody) at dilution 1/80.
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 214033(Anti-CASP9 (Anti-active) Antibody) at a dilution of 1/80.	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D161227(Anti-CASP9 (Anti-active) Antibody) at dilution 1/80.

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