NRG3 Rabbit pAb

214109

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S214109

Product Name: Anti-NRG3 Rabbit Polyclonal Antibody

Synonyms: HRG3; pro-NRG3

UNIPROT ID: P56975 (Gene Accession - NP_001010848 )

Background: This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4.

Immunogen: Synthetic peptide of human NRG3

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 214109(NRG3 Antibody) at a dilution of 1/30(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 214109(Anti-NRG3 Antibody) at dilution 1/30.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 214109(Anti-NRG3 Antibody) at a dilution of 1/30.	In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D161360(Anti-NRG3 Antibody) at dilution 1/30.
Gel: 6%SDS-PAGE, Lysate: 40 μg; Lane: Human fetal brain tissue; Primary antibody: 214109(NRG3 Antibody) at dilution 1/200; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 2 minutes

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NRG3 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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