CEBPB Rabbit pAb

214238

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S214238

Product Name: Anti-CEBPB Rabbit Polyclonal Antibody

Synonyms: LAP; CRP2; TCF5; IL6DBP; NF-IL6; C/EBP-beta

UNIPROT ID: P17676 (Gene Accession - NP_005185 )

Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

Immunogen: Synthetic peptide of human CEBPB

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 1000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse, Rat

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling, Cardiovascular

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 214238(CEBPB Antibody) at a dilution of 1/60(Nucleus and Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 214238(Anti-CEBPB Antibody) at dilution 1/60.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 214238(Anti-CEBPB Antibody) at a dilution of 1/60.	In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D161551(Anti-CEBPB Antibody) at dilution 1/60.

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