DHH Rabbit pAb

214288

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S214288

Product Name: Anti-DHH Rabbit Polyclonal Antibody

Synonyms: GDXYM; HHG-3; SRXY7

UNIPROT ID: O43323 (Gene Accession - NP_066382 )

Background: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Immunogen: Synthetic peptide of human DHH

Applications: ELISA, IHC

Recommended Dilutions: IHC: 50-200; ELISA: 2000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 214288(DHH Antibody) at a dilution of 1/25(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 214288(Anti-DHH Antibody) at dilution 1/25.
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 214288(Anti-DHH Antibody) at a dilution of 1/25.	In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D161623(Anti-DHH Antibody) at dilution 1/25.

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DHH Rabbit pAb

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