IFNGR2 Rabbit pAb

214399

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S214399

Product Name: Anti-IFNGR2 Rabbit Polyclonal Antibody

Synonyms: AF-1; IFGR2; IFNGT1

UNIPROT ID: P38484 (Gene Accession - NP_005525 )

Background: This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

Immunogen: Synthetic peptide of human IFNGR2

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 2000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Metabolism, Immunology, Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 214399(IFNGR2 Antibody) at a dilution of 1/40(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 214399(Anti-IFNGR2 Antibody) at dilution 1/40.
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 214399(Anti-IFNGR2 Antibody) at a dilution of 1/40.	In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D161776(Anti-IFNGR2 Antibody) at dilution 1/40.
Gel: 8%SDS-PAGE, Lysate: 60 μg; Lane: Mouse muscle tissue; Primary antibody: 214399(IFNGR2 Antibody) at dilution 1/200; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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