P2RX3 Rabbit pAb

214550

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

Add to cart

Download

Datasheet

MSDS

Product Description Reference citations(0) Related Products

Cat.#: S214550

Product Name: Anti-P2RX3 Rabbit Polyclonal Antibody

Synonyms: P2X3

UNIPROT ID: P56373 (Gene Accession - NP_002550 )

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Immunogen: Synthetic peptide of human P2RX3

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 25-100;WB: 200-1000;ELISA: 1000-2000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 214550(P2RX3 Antibody) at a dilution of 1/50(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 214550(Anti-P2RX3 Antibody) at dilution 1/50.
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 214550(Anti-P2RX3 Antibody) at a dilution of 1/50.	In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D161996(Anti-P2RX3 Antibody) at dilution 1/50.
Gel: 8%SDS-PAGE, Lysate: 40 μg; Lane 1-2: Human bladder tissue, Human bladder transitional cell carcinoma tissue; Primary antibody: 214550(P2RX3 Antibody) at dilution 1/250; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 10 minutes

Reference citations

No data available

Product Targets

Product Categories

P2RX3 Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

Contant Us