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MMP9 Rabbit pAb

214553

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S214553
Product Name:   Anti-MMP9 Rabbit Polyclonal Antibody
Synonyms:   GELB; CLG4B; MMP-9; MANDP2
UNIPROT ID:   P14780 (Gene Accession - NP_004985 )
Background:    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Immunogen:    Synthetic peptide of human MMP9
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 214553(MMP9 Antibody) at a dilution of 1/80(secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 214553(Anti-MMP9 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 214553(Anti-MMP9 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D161999(Anti-MMP9 Antibody) at dilution 1/80.
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