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SLC5A6 Rabbit pAb

214710

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   S214710
Product Name:   Anti-SLC5A6 Rabbit Polyclonal Antibody
Synonyms:   SMVT
UNIPROT ID:   Q9Y289 (Gene Accession - NP_066918 )
Background:    SLC5A6 is a 635 amino acid protein that belongs to the sodium-coupled glucose transporter family. SMVT contains 12 putative transmembrane domains with the N and C termini both facing towards the cytoplasm. Its function is to transport the essential vitamins pantothenate, biotin, and the metabolite lipoate into cells of various human tissues. Biotin, also known as vitamin B6, is important in synthesizing fatty acids gluconeogenesis, and metabolizing leucine, while pantothenate, or vitamin B5, is critical in the metabolism and synthesis of carbohydrates, proteins, and fats. Lipoate is involved in oxidative metabolism.
Immunogen:    Synthetic peptide of human SLC5A6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 214710(SLC5A6 Antibody) at a dilution of 1/20(Cytoplasm or Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 214710(Anti-SLC5A6 Antibody) at dilution 1/20.
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