TMPRSS11F Rabbit pAb

214805

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S214805

Product Name: Anti-TMPRSS11F Rabbit Polyclonal Antibody

Synonyms:

UNIPROT ID: Q6ZWK6 (Gene Accession - NP_997290 )

Background: TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.

Immunogen: Synthetic peptide of human TMPRSS11F

Applications: ELISA, WB, IHC

Recommended Dilutions: IHC: 25-100;WB: 500-2000;ELISA: 2000-5000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 214805(TMPRSS11F Antibody) at a dilution of 1/30(Cytoplasm).	In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 214805(Anti-TMPRSS11F Antibody) at dilution 1/30.
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 214805(Anti-TMPRSS11F Antibody) at a dilution of 1/30.	In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D162381(Anti-TMPRSS11F Antibody) at dilution 1/30.
Gel: 8%SDS-PAGE, Lysate: 40 μg; Lane 1-3: Human thyroid tissue, Human esophagus cancer tissue, human normal rectum tissue; Primary antibody: 214805(TMPRSS11F Antibody) at dilution 1/500; Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution; Exposure time: 1 minute

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TMPRSS11F Rabbit pAb

TUBB3 Rabbit pAb

GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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