RBFOX3 Rabbit pAb

215066

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S215066

Product Name: Anti-RBFOX3 Rabbit Polyclonal Antibody

Synonyms: FOX3; NEUN; FOX-3; HRNBP3

UNIPROT ID: A6NFN3 (Gene Accession - NP_001076044 )

Background: This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Immunogen: Synthetic peptide of human RBFOX3

Applications: ELISA, IHC

Recommended Dilutions: IHC: 25-100; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling, Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 215066(RBFOX3 Antibody) at a dilution of 1/20(Cytoplasm and Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 215066(Anti-RBFOX3 Antibody) at dilution 1/20.
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 215066(Anti-RBFOX3 Antibody) at a dilution of 1/20.	In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D162825(Anti-RBFOX3 Antibody) at dilution 1/20.

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RBFOX3 Rabbit pAb

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