HOXD3 Rabbit pAb

215133

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: S215133

Product Name: Anti-HOXD3 Rabbit Polyclonal Antibody

Synonyms: HOX4; HOX1D; HOX4A; Hox-4.1

UNIPROT ID: P31249 (Gene Accession - NP_008829 )

Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities.

Immunogen: Synthetic peptide of human HOXD3

Applications: ELISA, IHC

Recommended Dilutions: IHC: 20-100; ELISA: 5000-10000

Host Species: Rabbit

Clonality: Rabbit Polyclonal

Isotype: Immunogen-specific rabbit IgG

Purification: Antigen affinity purification

Species Reactivity: Human, Mouse

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol

Research Areas: Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 215133(HOXD3 Antibody) at a dilution of 1/25(Nucleus).	In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 215133(Anti-HOXD3 Antibody) at dilution 1/25.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 215133(Anti-HOXD3 Antibody) at a dilution of 1/25.	In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D162928(Anti-HOXD3 Antibody) at dilution 1/25.

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