Email Us：info@neweastbio.com
Call Us：(+1) 610-945-2007
Email Us：info@neweastbio.com
Call Us：(+1) 610-945-2007
Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N261522 |
| Product Name: Anti-SMC1A Mouse Monoclonal Antibody |
| Synonyms: Chromosome segregation protein SmcB; DXS423E; KIAA0178; MGC138332; Sb1.8; Segregation of mitotic chromosomes 1; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1 (structural maintenance of chromosomes 1 yeast) like 1; SMC1; SMC1 structural maintenance of chromosomes 1 like 1; SMC1A; SMC1A_HUMAN; SMC1alpha; SMC1L1; SMCB; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes protein 1A. |
| UNIPROT ID: Q14683 |
| Background: Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment. |
| Immunogen: Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli. |
| Applications: WB,ICC/IF |
| Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 |
| Host Species: Mouse |
| Clonality: Mouse Monoclonal |
| Clone ID: 4C5-C8-A11 |
| MW: Calculated MW: 143 kDa; Observed MW: 143 kDa |
| Isotype: IgG1 |
| Purification: Affinity Purified |
| Species Reactivity: Human |
| Conjugation: Unconjugated |
| Modification: Unmodified |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| Research Areas: Cell Biology |
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of SMC1A(Cterm) in K562, Jurkat, C6, 3T3 and Hela lysates using SMC1A (Nterminus) antibody. |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase
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