Pyruvate Dehydrogenase E1 alpha Mouse mAb

261523

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N261523

Product Name: Anti-Pyruvate Dehydrogenase E1 alpha Mouse Monoclonal Antibody

Synonyms: mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase (lipoamide) alpha 1; Pyruvate dehydrogenase complex; E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 component subunit alpha; Pyruvate dehydrogenase E1 component subunit alpha; somatic form; mitochondrial; somatic form.

UNIPROT ID: P08559

Background: The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Catalyzes the removal of CO2 from pyruvate. Mutations in the α subunits of pyruvate dehydrogenase (E1) lead to congenital defects that are usually associated with lactic acidosis, neurodegeneration and early death.

Immunogen: Purified recombinant human Pyruvate Dehydrogenase protein fragments expressed in E.coli.

Applications: WB,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200

Host Species: Mouse

Clonality: Mouse Monoclonal

Clone ID: 3H2-F8-B5

MW: Calculated MW: 43 kDa; Observed MW: 43 kDa

Isotype: IgG1

Purification: Affinity Purified

Species Reactivity: Human,Mouse,Monkey,Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of pyruvate dehydrogenase (lipoamide) alpha 1 in COS7, Jurkat, C6, 3T3 and Hela lysates using pyruvate dehydrogenase (lipoamide) alpha 1 antibody.

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