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SIRT2 (1D4) Mouse mAb

261038

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261038
Product Name:   Anti-SIRT2 (1D4) Mouse Monoclonal Antibody
Synonyms:   SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2
UNIPROT ID:   Q8IXJ6
Background:    Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.
Immunogen:    Purified recombinant human SirT2 protein expressed in E.coli.
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    1D4-H11-H11
MW:    Calculated MW: 43 kDa; Observed MW: 43 kDa
Isotype:    IgG2b
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of SIRT2 (1D4) in Hela using SirT2 antibody(green) and Histone H3.1 (Phospho-Ser10) (310045) antibody(red).

Western blot analysis of SirT2 in PC-12, rat Brain and mouse Brain lysates using SirT2 antibody.

Western blot analysis of SIRT2 (1D4) in rat Cerebral Cortex and rat Brain lysates using SirT2 antibody.
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